Sandrine Ongeri, Benoit Crousse, Léa Radal
The third work package aims to select of a subset of suitable aptamers on the basis of their biochemical properties. The aptamers will be produced, analysed and biochemically characterized.
The work package is divided in 3 tasks:
Task 3.1: Aptamer synthesis.
Tasks 3.2: Validation of aptamers targeted against cell wall biosynthetic enzymes.
Task 3.3: Synthesis of peptidomimetics derived from peptide aptamers.
The seventh work package aims to select peptidomimetics and non-peptide small molecules for pathogen control through the analysis of their biological activity, specificity and toxicity.
The work package is divided in 2 tasks:
Task 7.1: Bioactivity of peptidomimetics and non-peptide small molecules.
Task 7.2: Specificity and Toxicity.